GLP-1 Patients: How to Preserve Muscle Mass

GLP-1 medications like semaglutide and tirzepatide are game-changers for metabolic health. One common concern we hear at the counter every week: I don't want to lose muscle. Smart thinking — the science backs you up.

Dr. Mike Israetel has been crystal clear: prioritize protein and resistance training to protect lean mass. Higher protein intake combined with lifting helps you lose fat, not muscle.

The Practical Protocol

• Protein target: 1.6–2.2g per kg of body weight daily. Spread across meals.
• Resistance training: 2–4 sessions per week with progressive overload.
• Creatine: Most researched supplement for muscle preservation. 3–5g daily, no loading required.
• Don't undereat protein — this is where protein shakes earn their place.

Why This Matters More on GLP-1s

GLP-1 medications suppress appetite significantly. The risk: you end up in a large caloric deficit without realizing your protein intake has cratered. The goal isn't just weight loss — it's body recomposition. Less fat, same or more muscle.

The Vuzzy GLP-1 Support Stack

• Whey Protein Isolate (Chocolate) or Vanilla — NSF Certified for Sport, fast-absorbing, high biological value.
• Creatine by Thorne — NSF Certified, micronized, same formula used by NBA and NFL teams.
• Basic Nutrients 2/Day — comprehensive multi because eating less means micronutrient gaps become real.
• GLP-1 Support Stack (Berry) or Lemon — nutrients formulated specifically for GLP-1 patients.

Come talk dosing and timing with us at VitaScripts Pharmacy. We work with GLP-1 patients every day. Browse vuzzy.com.

Not medical advice. Work with your prescribing provider and a qualified trainer.